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  • Park
    Atomic Force Microscope
    The most accurate and practical
    nano bio-research microscope

Single Live Cell Imaging and Scanning Ion Conductance Microscopy

Park XE-Bio is a powerful 3-in-1 bio-research tool that uniquely combines Scanning Ion Conductance Microscopy (SICM) with AFM and inverted optical microscope (IOM) on the same platform. The modular design of Park XE-Bio allows easy exchange between SICM and AFM. Designed for non-invasive in-liquid imaging, the combined bio-mechanical property measuring capability of AFM, SICM, and inverted optical microscopy makes Park XE-Bio ideal for studying biological materials under physiological conditions.

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Powerful 3-in-1 Nanoscale Research Tool with Modular Platform

  • Scanning Ion Conductance Microscope (SICM)
  • True Non-Contact mode Atomic Force Microscope (AFM)
  • Inverted Optical Microscope

Non-invasive In-liquid Imaging by SICM

  • Monitoring ion channels of single living cells
  • Unique functional capability of targeted localized stimulation
  • Enable nanoscale patch-clamping for electrophysiology
  • Environmental chamber for temperature, pH, and humidity control

Ultimate AFM Resolution by True Non-Contact ModeTM

  • 10 times larger Z-scan bandwidth than a piezotube
  • Less tip wear for prolonged high-quality and high-resolution imaging
  • Minimized sample damage or modification
  • Immunity from parameter-dependent results observed in tapping imaging
  • Single molecule Force-Distance spectroscopy with automated data analysis

Fully Integrated Inverted Optical Microscope

  • Compatible with phase contrast and DIC imaging
  • Also compatible with fluorescence microscopy
  • Advanced image overlay functions

Park XE-Bio Scanning Ion Conductance Microscope - Overview